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If you didn’t realize by now, SelfHacked specializes in complex topics and we have many references per a post -sometimes over 100. It probably looks easier than it seems to get good original content out.

In order to release the best content, we are implementing a new system that will improve our process to increase the accuracy of the content. We haven’t been as rigorous in the past, but going forward we will be.

Before we release any post to the front page, we are going to put it through our own internal review process.  We are working some stealth published posts that aren’t up to our standards.

First, how we pick our writers….

  1. Our writers must have a science background.
  2. We put all of our writers through cognitive tests that ensure they can read and rationalize effectively with complex content.
  3. We then give them some sample posts and see how they do. If they reference something that doesn’t match the study they are citing, we boot them as a writer.

Once they write the article it goes through our internal peer review process:

  1. 2 biohackers read through it and make edits/corrections
  2. First scientist (PhD) reads through it and makes edits/corrections
  3. Second scientist (PhD) reads through it and makes edits/corrections
  4. And then Joe reads through it and makes edits/corrections

We have updated the team page.

FDA Compliance

The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.


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  • alexgierczyk

    Have you looked at using a plugin like Disqus for comments?

    It’s very popular. It gives you features like voting on comments, powerful moderation tools, granular control on notifications, and a lot more. It’s also better integrated with social media than comments.

    1. Joseph M. Cohen

      It was buggy when I last tried it

  • Alex

    Hi Joe. Just to let you know that there are some issues with websites when you try to search or look at the equipment, supplements, etc. Everything seems to be misplaced then both on chrome and IE. Also, many of the links from equipment page do not work (I am looking at stationary bright light devices and only one of the three links work on both of my computers).

    1. Joseph M. Cohen

      Thanks Alex!

      I fixed the links…If any links are broken, let me know….I reorganized the links by supplements and equipment rather than where to buy them…I’m basically finished with that…

      Hope all is well 🙂

  • Steve

    Be careful with the 23andme. They’re obviously not making money on the kit itself, which leads me to believe the database will be up for bidding later: insurance, pharma companies, anyone who pays. Food for thought.

    Put the kit on someone else’s credit card and use a fake name. You don’t want to wake up one day to Google knowing more about you than you know yourself.

  • Kyle

    Any thoughts on calcium 2-aep?

  • Nina Chrumov

    Could you explain the rationale behind purchasing different types of LLLTs? what types?

  • smurfed

    Does he know of any systems in development which could have a manipulatory effect on neuronal signalling, particularly GABA in the near future?

  • Josh S.

    Dr. Dennis: What is the minimum amount of time ICES needs to be used to feel therapeutic effects for soft tissue injuries? IE is half hour every other day enough ?

  • dave

    Somewhat unrelated (didn’t know where to post) – have you experimented with smelling caffeine? I react really badly to drinking coffee but when I smell coffee ( especially when working at PEETS coffee where they a have really strong smell), I get really good cognitive improvement and good mood, does it make sense?

    1. dave

      I started making huge bowel of good coffee and putting it in the room for smell and the effect remains

  • Ellamo

    Ask Dennis:

    – what is his view of EMFs and their effect on health.

    – Why does this device really work (still unclear)?

    1. lordlol

      second to that.
      those are questions i am interested in as well.

  • thepractice

    Questions for Dr. Dennis about the ICES device: what frequencies does it operate at? says 10 hz and 100 hz. Can you explain the low, medium, high, extra high settings? please discuss local vs systemic effects of coil placement. What placement would u recommend for overall general health? For mental health. Is it safe to use near a computer? What limits or contraindications would u suggest for safety?

    Thanks joe

  • DeltruS

    What do you think of this post?

    I know that you say inflammation of the hypothalamus is the biggest cause of fatigue. And inflammation should cause brain shrinkage. So the reveal that CNTF increases neurogenesis in this area should be a pretty big deal.

    1. Joseph M. Cohen


  • orangothom

    How’s the book coming along?

  • cross.chrono

    Looking forward to your book!

  • Adrian

    Hi Jo. I believe your timing is serendipitous. Literally just started reading “PEMF – The Fifth Element of Health: Learn Why Pulsed Electromagnetic Field (PEMF) Therapy Supercharges Your Health Like Nothing Else!”

    The guy who wrote this, claims to have spent over $500,000 on all sorts of devices, so looking forward to seeing what happens.

    I did around 2 years ago buy the SOTA magnetic pulser and still use that for any muscle aches or pains.

  • Deltrus

    Quick question:

    Are orexin + BDNF suppression the primary reasons that inflammation lowers cognition? Would it be possible to use some drug to modulate orexin/BDNF, and just throw out trying to change the immune system?

    Or are there a very wide variety of reasons?

    1. Joseph M. Cohen

      Wait for the book

      1. Deltrus

        Ok ty 🙂

  • lordlol

    what so good about feeling in love?
    i dont even remember how it feels, no do i remember it was unique?
    you might be crazy.

  • Deltrus

    I will 100% buy your book! It amazes me that you are the only guy doing research on this kind of stuff. I would be so miserable if the answers were out of reach. I am so glad I wasn’t born 20 years earlier.

    I tried potato starch recently and it felt great the on the second day. However, with each day I got cumulatively worse cognition and fatigue. This makes me think I have lectin intolerance. It was also very cool because I felt a very smooth ramp of of my symptoms, which allowed me to isolate how they “feel”.

    My 23andme kit should arrive there in ~1 week. I will probably use both your service and also ask Misteryouaresodumb to analyze it for me. (I’l have to give him a donation since it would feel bad buying yours but getting his free)

    I’m just trying to figure out what to do for a lectin free diet. It is a real shame there isn’t an easy cure for lectin sensitivity yet.

    Maybe my 23andme test will give me some easy cures. That would be amazing. I hope I have some bad mutation such as a MTHFR, because you can supplement for that.

    1. Joseph M. Cohen


  • Aaron

    I also experimented with and found a chemical that induces love-like euphoria in me – and I bet you know just what it is 🙂

    1. Aaron

      Also for some people lots of activities induce the same euphoria, like rock climbing or extreme sports or traveling or partying. There is nothing unique or irreplaceable about love despite what the women would have us believe in their attempts to snare us 🙂 Love is just one good experience, and not necessarily the best.

  • Ursula

    Sounds like you’re going a little psychotic, Joe!

  • socraticstoic

    I would just say please try to write your book in a way that dumb people like me will “get it.”

    1. Joseph M. Cohen


    2. Joseph M. Cohen

      I’ll send you the rough draft when it’s ready and you’ll tell me if it’s too technical.

      1. socraticstoic

        Would love to help in any way I can.

  • Paul

    Hey, your blog has helped me immensely in my quest to beat my health problems. I really appreciate your objectivity and lack of nonsense.
    Really looking forward to reading your book!

    1. Joseph M. Cohen

      Thanks 🙂

  • Alex

    Yeah. I wondered so many times whether it’s just placebo that is in work, but when you literallly can see an effect (on skin eg.) it’s hard to believe that it would be just placebo. Though, human psychology is crazy, so we will never now, unless someone did a crazy well-designed, double blind study on good quality supplements, rather than on the cheap crap that is sold in chains.

  • Brian

    In your new regimen how much olive oil are you consuming per day? Is there a particular macro you stick to?

  • Stephen

    Any Birch Bark / Betulin Thoughts ?

  • Steve

    I did tDCS on the DLPFC for two months at 2mA for 20 minutes/day, but had to stop at a point since I started getting massive OCD, I thought I had damaged this part of the brain, I also managed to burn my right biceps with one of the electrodes, which left me with a deep scar.

    I’ll try again in the future however.

  • John


    Have you determined a hack for your SOD2 Polymorphisms? I think supplementing with the manganese cofactor or tocotrienols can be detrimental in the abscense of a deficiency. I have been searching for clues as I have 3 homozygous SOD2 polymorphisms.

    1. Joseph M. Cohen


  • Marco

    What do you think of red light therapy with incandescent or near infrared bulbs?

  • Alex

    Good to hear about DNA consulting! 🙂 Soon after graduation I will go on and do the 23andMe then. Btw. do you have the price set for this service?

    1. Joseph M. Cohen

      Not yet 🙂

  • Dylan

    Sounds good. There’s allot of services out there, but they are mostly cut and paste, such as nutrahacker. A truly individualized interpretation would be valuable.

  • Alex

    Hi Joe! I’m wondering what you think of sauna, and ice-cold baths/showers?

  • Ole

    B12 for sleep is a bad idea i think.
    “The presence of vitamin B-12 helps boost the response to external light and turn off melatonin signaling in your brain, helping your brain make the transition from a resting sleep state to a more active awake state.
    A study published in “Neuropsychopharmacology” in November 1996 found that methylcobalamin vitamin B-12 supplements could increase alertness at night, aiding in sleep reduction and the capacity for activity at night. Taking supplements containing methylcobalamin at night might alter your sleep cycle. If you take the supplements over a long period, you might develop sleep deprivation.”

    1. Joseph M. Cohen

      Give me the link. I don’t think it’s a good idea in general, but it worked for me for one night. Theoretically, I agree with you, though.

      1. Dalamar

        I take 5 mg of methylcobalamin in the mornings and increases alertness in my case.

  • Rachel

    I have MTHFR mutation. Did you notice any benefit from tossing N yeast? What is your current source for B vitamins now? Multivitamins?

  • Rollia

    Do you separate types of potassium equally?

  • Rollia

    What about your prospect to develop oral tolerance to eggs? how would it fit with your new regimen?

  • dave

    Will ketosis be doable on your new regimen?

    1. Joseph M. Cohen

      I’m shelving the ketosis experiments aside for now. I will reintroduce it later.

  • dave

    If you do not feel any negative reaction from chicken and cod, why chopping them from your diet? It sounds like a theoretical and dogmatic approach you are against…

    1. Joseph M. Cohen

      no dogma at all. I noticed I do better without chicken, at least in the short term (a week). I haven’t tried to rid cod yet, but I always got a little fatigued after it. Was worth it bec it makes me feel good, too. Same w/ chicken.

      1. dave

        Thank you! What will be your new source of DHA? If cod liver makes you feel good, why toss?

        1. Joseph M. Cohen

          It also makes me a bit sleepy for 15 minutes. I also don’t like that it’s in a can and that it’s the liver of a fish, which means that’s where the toxins are found. I wonder if I’m getting a bit sleepy from it as a result of the toxins.

          I’m going to experiment w/ dif fish oils. I may come back to it if none can replace it.

          1. BB

            Hey Joe, have you tried DHA and EPA made from algae?

            reply icon
  • Dalamar

    Another supplement that could be very interesting is Nicotinamide Ribose that is getting very popular now and some people mention that they can get very strong effects.

    Do you know this blog? The blog is a bit messy the guy mentions that experimenting with high doses of suplements he managed to improve a lot physically and look much younger:

    1. Joseph M. Cohen

      If you mean nicotinamide riboside, I’ve been taking it for over 6 months and mentioned it on the blog several times.

  • Dalamar

    It will be interesting if you can enumerate the genes related to Chron’s, usually Chron’s gets triggered by stress, I know a few cases that it started after a very stressful event in live, then take it easy and meditate…

  • Alex

    Joe, I am wondering how do you do your own investigation when it comes to 23andme data. I am still hesitant to orer ther kit, since (from what I have seen) they do not provide much information in terms of susceptibility to diseases. I may be wrong since I have not seen their results myself, but that’s what I have heared. Have you did your own investigation by looking at publications, etc. and looking for SNPs which seems to be increased in people with specific problems?
    I would appreciate your answer.

    1. Joseph M. Cohen

      I use promethease, but mostly it’s intense reading of the publications – sometimes the entire studies. So the answer is to really understand what’s going on you have to do some reading.

      If you don’t have an extensive scientific background, it’s going to be very challenging to understand what’s going on, but I plan on making it easier for people. See me articles on MAOA and COMT.

      1. Alex

        Thanks! I guess if you made series of posts for people, it would be really popular (if properly advertised). Especially now that 23andMe is back and running in UK.

        1. Joseph M. Cohen

          Genetic information will be a significant portion of the content produced on this blog, so you might want to get it done.

  • lordlol

    hi do you have C60 post?

  • Stuart

    Good to hear about Hi-Maize!

    There’s also a cheap DIY PEMF if you (or anyone is interested):

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