Luteolin is an important phytochemical found in many foods. Its health benefits range from possibly preventing cancer to protecting the brain. Read more below to find out how you can improve your health with the help of luteolin.
- Introduction to Luteolin
- The Luteolin That I Take
- Health Benefits of Luteolin
- 1) Luteolin Fights Cancer
- 2) Luteolin Decreases Inflammation
- 3) Luteolin is an Antioxidant
- 4) Luteolin is a Natural Sun Protectant
- 5) Luteolin Improves Heart Function
- 6) Luteolin Protects the Brain From Neurological Impairments
- 7) Luteolin is an Antiviral
- 8) Luteolin Prevents Cataracts
- 9) Luteolin May Be Therapeutic for Multiple Sclerosis
- 10) Luteolin Inhibits Mast Cells
- 11) Luteolin Has Anti-Depressant Effects
- Negatives/Cons of Luteolin
- Buying Luteolin Supplements
- Food Sources of Luteolin
- Health Tools I Wish I Had When I Was Sick
Introduction to Luteolin
Luteolin is a flavonoid found in many types of plants including fruits, vegetables, and medicinal herbs. It is known for its many health benefits. [R]
Flavonoids are common nutrients that are antioxidants and antimicrobial agents. [R]
The Luteolin That I Take
Luteolin is not absorbed very well, so I like to take it with something that has a range of flavanoids.
Health Benefits of Luteolin
Although Luteolin is absorbed in humans (R).
1) Luteolin Fights Cancer
It inhibits the growth of new blood vessels in tumors, the metabolism of carcinogens, as well as stopping the progression of the cell cycle in cancer cells. Luteolin also induces cell death in cancer cells. [R]
Luteolin inhibited the incidence rate of tumors and decreased the size of tumors significantly. [R]
Long term treatment did not show any apparent toxicity in rats at a dose of 30mg/kg, implying that luteolin is relatively safe as an anticancer agent. [R]
2) Luteolin Decreases Inflammation
Experiments with animals show that luteolin suppresses bacteria-induced inflammation. [R]
Luteolin suppressed pro-inflammatory marker expression and cytokine expression in LPS-activated microglia. [R]
In an experiment on rats with toxin-induced uveitis, luteolin had great success in anti-inflammatory treatment, comparable to that of prednisolone. [R]
Luteolin can also inhibit colitis (inflammation in the colon). [R]
3) Luteolin is an Antioxidant
Luteolin significantly induces genes related to antioxidant defense. [R]
4) Luteolin is a Natural Sun Protectant
5) Luteolin Improves Heart Function
Luteolin substantially increased cell life while reducing evidence of oxidative stress-induced damage in the cells. [R]
6) Luteolin Protects the Brain From Neurological Impairments
Tests on flies expressing a neurological impairment that resembles amyloidosis showed that luteolin rescued the impairment. [R]
Luteolin can go through the blood-brain-barrier (BBB), which shows anti-amnesic effects against the toxicity of amyloid in mice. [R]
Luteolin also protects against high-fat diet-induced cognitive defects in obesity mice. [R]
Luteolin was found to have potent antiviral activity against Japanese encephalitis virus (JEV). [R]
Luteolin reduced the number of Epstein-Barr virus reactivating cells and reduced the production of the virus. It does this by repressing the activities of the promoters of the immediate-early genes Zta and Rta. [R]
In mice with hepatitis B virus (HBV), Luteolin reduced HBV DNA replication, suggesting that it may be used for anti-HBV therapy. [R]
8) Luteolin Prevents Cataracts
In rats, luteolin enhanced the antioxidant potential and lowered the oxidative damage to the lens’ of rats in selenite-induced cataracts. It also improved the membrane integrity of the lens. [R]
9) Luteolin May Be Therapeutic for Multiple Sclerosis
Multiple Sclerosis is a disease that affects the immune system – nerve damage causes pain and fatigue. Luteolin has anti-oxidant and anti-inflammatory effects which can reduce the effects of multiple sclerosis [R].
10) Luteolin Inhibits Mast Cells
Luteolin inhibits mast cells and mast cell-dependent T cell activation, factors which contribute to multiple sclerosis [R].
In this way, it can also help with histamine intolerance.
11) Luteolin Has Anti-Depressant Effects
The endoplasmic reticulum in a cell can undergo stress, which can cause cell death. In the brain, neuronal cells undergo cell death and this can cause symptoms of depression.
Luteolin significantly suppresses cell death by relieving endoplasmic reticulum stress. [R]
Negatives/Cons of Luteolin
1) Luteolin Disrupts Endocrine Activity
2) Luteolin Can Aggravate Colon Inflammation
While luteolin can help stop spontaneous colitis, it can also increase the effects of dextran sodium sulfate (DSS)-induced colitis. It blocks protective molecules in intestinal cells which prevent inflammation in the colons due to DSS. [R]
Buying Luteolin Supplements
Luteolin is not absorbed very well, so I like to take it with something that has a range of flavanoids:
Food Sources of Luteolin
Luteolin is found commonly in a bunch of plants, specifically vegetables.
Food sources include: carrots, artichoke, peppers, celery, olive oil, peppermint, thyme, rosemary, oregano, etc. [R]
Health Tools I Wish I Had When I Was Sick
At SelfHacked, it’s our goal to offer our readers all the tools possible to get optimally healthy. When I was struggling with chronic health issues I felt stuck because I didn’t have any tools to help me get better. I had to spend literally thousands of hours trying to read through studies on pubmed to figure out how the body worked and how to fix it.
That’s why I decided to create tools that will help others cut down the guesswork:
- Lab Test Analyzer – a software tool that will analyze your labs and tell you what the optimal values are for each marker — as well as provide you with actionable tips and personalized health and lifestyle recommendations to help you get there.
- SelfDecode – a software tool that will help you analyze your genetic data from companies such as 23andme and ancestry. You will learn how your health is being impacted by your genes, and how to use this knowledge to your advantage.
- SelfHacked Secrets – an ebook where we examine and explain the biggest overlooked environmental factors that cause disease. This ebook is a great place to start your journey if you want to learn the essential steps to optimizing your health.
- SelfHacked Elimination Diet course – a video course that will help you figure out which diet works best for you
- Selfhacked Inflammation course – a video course on inflammation and how to bring it down
- Biohacking insomnia – an ebook on how to get great sleep
- Lectin Avoidance Cookbook – an e-cookbook for people with food sensitivities
- BrainGauge – a device that detects subtle brain changes and allows you to test what’s working for you
- SelfHacked VIP – an area where you can ask me (Joe) questions about health topics
The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.
HOW WOULD YOU RATE THIS ARTICLE?