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Luteinizing hormone stimulates the testes in males and the ovaries in females. This hormone is vital for Reproductive health.

If you are struggling with chronic health issues – the way I used to – you probably have piles of lab tests that can potentially tell you a lot about your health. Luteinizing hormone may be one of them. However, doctors never had enough time to explain it properly. They will only notice it if the lab flags your test results as outside of normal. But what if all your results are coming back normal, yet you know you are feeling nowhere near healthy? They may even tell you there is nothing wrong with you, and that it’s all in your head – I’ve been there.

Lab Test Analyzer is the tool I wish I had when I was dealing with all my health issues. Instead of normal, it will tell you the optimal values for luteinizing hormone and many other lab tests. And if you are outside the optimal range, it will give you actionable tips and recommendations that will help you get there.

Introduction to Luteinizing Hormone

Luteinizing hormone (LH) a hormone released by the pituitary gland in response to luteinizing hormone- releasing hormone (LHRH) (R). LHRH is released from the hypothalamus.

LH is a gonadotropic hormone and controls the functions of the female ovaries and male testes. It is also essential for proper reproductive function.

In males, it is also called the Interstitial cell stimulating hormone (ICSH) (R).

In general, when estrogen and progesterone levels fall, LH levels rise. Follicle Stimulating Hormone (FSH) is synergistic with LH.

In Women

In women, luteinizing hormone (LH) carries out different roles in the two halves of the menstrual cycle.

In weeks 1-2 of the cycle LH is required to stimulate the ovarian follicles in the ovary to produce the female sex hormone, oestradiol.

Later a “surge” in LH levels causes Ovulation. In the remainder of the cycle, LH stimulates the corpus luteum to produce progesterone which is required to support the early stages of pregnancy, if fertilization occurs (R).

In Men

Luteinizing hormone stimulates Leydig cells in the testes to produce testosterone. If testosterone levels decrease, LH secretion increases. This is known as negative feedback.

Testosterone, in turn, stimulates sperm production as well as generating male characteristics throughout the body (R).

Effects of Luteinizing Hormone

1) Luteinizing Hormone and Depression

Major depressive disorder is associated with abnormal regulation of LH (R).

2) Photoperiod Alters Luteinizing Hormone Secretion

A study found that dark-deprivation (photoperiod disruption) increased LH levels in fetal circulation but not in maternal circulation (R).

This study sheds new light on how circadian photoperiod disruption during pregnancy could alter the release of certain hormones into the fetal blood.

3) Luteinizing Hormone Helps Induce Ovulation

Ovine and human LH were good substitutes for hCG (Human Chorionic Gonadotropin) for induction of ovulation in female frogs (R).

4) Luteinizing Hormone and Alzheimer’s

In elderly women (postmenopausal), an increase in LH levels can lead to Alzheimer’s Disease development. Treatment with Gonadotropin release hormone agonists could provide benefits (R).

However, research is still in its preliminary stages and many questions remain unanswered.

5) Effect of Luteinizing Hormone on Glucose Metabolism

An increase in glycolytic activity and mitochondrial glucose oxidation is seen in bovine oocytes cultured with LH (R).

Elevated LH Levels

Elevated LH levels had adverse effects in multiple studies.

Women with an LH level greater than one standard deviation above the mean have a decrease in the rate of fertilization (R).

Patients with Polycystic Ovary Syndrome (POS) have a high pulsatile level of LH (R).

High LH levels are seen in genetic conditions such as Klinefelter’s syndrome. Klinefelter’s syndrome shrinks your testes and causes them to not produce enough testosterone for sperm production (R).

Reduced LH Levels

Low levels of LH will limit sperm production and can cause infertility.

Kallmann’s syndrome is caused by a deficiency in gonadotropin-releasing hormone (i.e., LHRH). It can result in a lack of sexual development, a small penis, undeveloped testes, and a delay in or lack of puberty (R).

In women, low levels of luteinizing hormone can lead to low levels of estrogen and improper development of corpora lutea (R).

Luteinizing Hormone (LH) Test

An LH test measures the amount of Luteinizing Hormone in the sample of blood or urine. It may be done to find the cause of a couple’s inability to become pregnant. LH test is commonly used to evaluate (R).

  • A women’s egg supply (ovarian reserve)
  • A man’s sperm count
  • menstrual problems in women.
  • a women’s response to medicines taken to stimulate ovulation.

You can request that your doctor test your luteinizing hormone. Conventional doctors will look at high or low luteinizing hormone levels and not mention anything. Sometimes, a lab result may be in the reference range, but not actually be in the optimal range. Reference ranges are not the same as optimal ranges. This is why even luteinizing hormone in the ‘normal’ range can be unhealthy and indicate that certain processes in the body aren’t optimal. Lab Test Analyzer will let you know if your luteinizing hormone levels are optimal and what you can do to get them there if they aren’t.


  • Hypogonadism is caused by the substitution of a single amino acid in the beta subunit of LH (R1, R2).
  • Luveris is the first and only recombinant human Luteinizing hormone (r-hLH) approved in the world (R).

Irregular Luteinizing Hormone Levels?

If you have not yet tested your luteinizing hormone levels, I recommend that you ask your doctor to do it. If you already have your blood test results and you’re not sure what to make of them, you need to check out Lab Test Analyzer. It does all the heavy lifting for you. No need to do thousands of hours of research on what to make of your various blood tests.

People don’t realize that their blood test results contain a gold mine of information that’s waiting to be unearthed. Unfortunately, not everyone has the time or the inclination to sift through dozens of research papers.

It’s super-simple, so that even if you don’t have any background in science, you will understand what your results mean and what you can do to get them in the optimal range.

Lab Test Analyzer gives you up-to-date scientific information about your lab results. In addition, you will get both lifestyle tips and natural solutions to help you optimize your health. You can also rely on our science-based Optimal Ranges to prevent potential health issues and maximize your overall well-being.

All of the content is backed by science and researched by a team of PhDs, professors, and scientists.

We’re all unique, so we deserve solutions that treat us that way.

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The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.


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  • Richard A Alberts

    in 1963..I was diagnosed with “low Iron”..since then..we’ve found it to be low “T” testing shows LH ..not working..not telling the testicles to make testosterone..nor sperm..( I was the first in North America to score zero on a testosterone check)
    anything out there to make the luteinizing hormones work?

  • Howard

    I was also unimpressed with that section of the article. What is a better resource for understanding LH/HCG relevant to a hypogonadic male?

  • john

    In the “Elevated LH” levels section, the study you cite as evidence for adverse effects (Klinefelter’s) states: “Both LH and FSH levels were suppressed by acute or prolonged testosterone administration and there was no evidence for a differential effect on LH”
    LH would be naturally suppressed by negative feedback with testosterone. In fact, in all the studies you present in this section, high LH levels are the result of other conditions the body is trying to fix!

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