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Vitamin B3, also known as niacin, is found in most foods. It has many beneficial effects on our health – it lowers cholesterol, protects the brain, helps keep the heart healthy, and improves the skin. Read more below to find out more about this powerful substance.
- Introduction to Vitamin B3/Niacin
- Health Benefits of Niacin
- Technical Section
- Sources of Vitamin B3/Niacin
- Side Effects
- Buy Niacin
- Health Tools I Wish I Had When I Was Sick
Introduction to Vitamin B3/Niacin
Vitamin B3 consists of two molecules: nicotinamide and nicotinic acid – sometimes collectively termed “niacin” (R).
Niacin improves cardiovascular health and reduces cholesterol, improves circulation, and suppresses inflammation. Most people get their recommended daily intake of Vitamin B3 from their diet. If you’re interested in a supplement that provides a full package approach to superior cognitive function and health, we recommend Qualia, which contains Vitamin B3 and many other great brain boosting ingredients. Use the coupon code ‘selfhacked’ and get 10% off a 1 time order or 15% off of a recurring order.
Health Benefits of Niacin
1) Niacin Lowers Cholesterol
Niacin can lower cholesterol in many ways.
2) Niacin Improves Heart Health
Taken daily with each meal, niacin prevents coronary heart disease events like non-fatal heart attacks and death (R).
The same study also found that niacin is protective in that niacin may halt or even reverse artery disease progression (R).
One study on humans showed that compared to the placebo group, niacin therapy significantly reduced coronary artery disease and nonfatal heart attacks (R).
3) Niacin Protects the Brain After a Stroke
A study on rats found that niacin is neuroprotective after a stroke (R).
Niacin therapy has also been shown to significantly reduce the chance of a stroke occurring (R).
4) Niacin Has Anti-Inflammatory Properties
It has been found that 1-methylnicotinamide, a metabolite of nicotinamide, possesses significant anti-inflammatory properties. Daily treatment resulted in reduced inflammation symptoms (R).
5) Niacin Improves Skin
Niacin substantially accelerated healing processes of burned skin (R).
When applied topically to the skin, niacin reduces fine lines and wrinkles, redness, and skin yellowing (R).
Niacin also improves skin elasticity (R).
6) Niacin May Promote Longevity
Niacin increase NAD+ concentrations which could confer pro-longevity effects (R).
- The level of hs-CRP decreased significantly in patients treated with niacin for 1 month (R).
- GPR109A,a niacin receptor, seems to mediate anti-lipolytic, anti-inflammatory, and antiatherogenic effects of niacin (R).
- Niacin binds to adipocyte membrane-bound GPR109A, thereby inhibiting adenylyl cyclase, lowering intracellular cAMP concentrations, and subsequently reducing protein kinase A-mediated activation of hormone-sensitive lipase (HSL) (R).
- It directly inhibits hepatocyte Acyl-CoA: diacylglycerol acyltransferase 2, a key enzyme catalyzing the terminal step in hepatic triglyceride synthesis (R).
- Niacin retards apoB-100 production rates, thus limiting LDL production (R).
- Niacin was recently found to inhibit proprotein convertase subtilisin-like/Kexin-type 9, a protease which accelerates hepatic LDL-receptor degradation and increases LDL-cholesterol (R).
- Increases Adiponectin levels (R).
- Increases Leptin levels (R).
- Increase in Ketone Bodies (R).
- Reduces HIF-1a expression (R).
- The increase of PPARa and PPARy expression in adipocytes (R).
Sources of Vitamin B3/Niacin
You can meet all of your body’s needs for B3 through diet. Niacin is most abundant in meat, eggs, fish, dairy products, certain vegetables, and whole wheat (R).
Vitamin B3 deficiency can cause many problems.
Symptoms of mild Vitamin B3 deficiency include:
- Canker sores
- Poor circulation
Severe deficiency can cause a condition known as pellagra, which is characterized by skin problems, diarrhea, and mental problems (R).
The recommended daily allowance of niacin is 16mg daily in adult men and 14mg daily in adult women, which can easily be obtained from a normal diet since vitamin B3 can be found in all animal, plant, and fungal food sources (R).
For supplementation, several studies used 1 Gram, administered three times a day with meals (R).
At high doses, niacin can be toxic. You should not take doses higher than the Recommended Daily Allowance (RDA) except under your doctor’s supervision (R).
If you’re interested in a supplement that provides a full package approach to superior cognitive function and health, we recommend Qualia, which contains Vitamin B3 and many other great brain boosting ingredients. Use the coupon code ‘selfhacked’ and get 10% off a 1 time order or 15% off of a recurring order.
Flushing of the face is the most common side effect. Flushing can result cause burning, tingling, itching, and redness of the face, arms, and chest, as well as headaches (R).
An overdose of niacin can cause thrombocytopenia or low blood platelet count. This causes bruising and blood to bleed into tissues (R).
Although there is no evidence that taking large doses of niacin can let you pass drug tests, there have been people who tried doing so. Niacin toxicity caused organ failures, fever, skin problems, and other disorders (R).
Health Tools I Wish I Had When I Was Sick
At SelfHacked, it’s our goal to offer our readers all the tools possible to get optimally healthy. When I was struggling with chronic health issues I felt stuck because I didn’t have any tools to help me get better. I had to spend literally thousands of hours trying to read through studies on pubmed to figure out how the body worked and how to fix it.
That’s why I decided to create tools that will help others cut down the guesswork:
- Lab Test Analyzer – a software tool that will analyze your labs and tell you what the optimal values are for each marker — as well as provide you with actionable tips and personalized health and lifestyle recommendations to help you get there.
- SelfDecode – a software tool that will help you analyze your genetic data from companies such as 23andme and ancestry. You will learn how your health is being impacted by your genes, and how to use this knowledge to your advantage.
- SelfHacked Secrets – an ebook where we examine and explain the biggest overlooked environmental factors that cause disease. This ebook is a great place to start your journey if you want to learn the essential steps to optimizing your health.
- SelfHacked Elimination Diet course – a video course that will help you figure out which diet works best for you
- Selfhacked Inflammation course – a video course on inflammation and how to bring it down
- Biohacking insomnia – an ebook on how to get great sleep
- Lectin Avoidance Cookbook – an e-cookbook for people with food sensitivities
- BrainGauge – a device that detects subtle brain changes and allows you to test what’s working for you
- SelfHacked VIP – an area where you can ask me (Joe) questions about health topics
The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.
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